AtRTP5 negatively regulates plant resistance to Phytophthora pathogens by modulating the biosynthesis of endogenous jasmonic acid and salicylic acid

摘要

Plants have evolved powerful immune systems to recognize pathogens and avoid invasions, but the genetic basis of plant susceptibility is less well‐studied, especially to oomycetes, which cause disastrous diseases in many ornamental plants and food crops. In this research, we identified a negative regulator of plant immunity to the oomycete , ( Resistant to 5), which encodes a WD40 repeat domain‐containing protein. The AtRTP5 protein, which was tagged with green fluorescent protein (GFP), is localized in the nucleus and plasma membrane. Both the T‐DNA insertion mutants and the ( ) silencing plants showed enhanced resistance to , while overexpression of rendered plants more susceptible. The transcriptomic analysis showed that mutation of suppressed the biosynthesis of endogenous jasmonic acid (JA) and JA‐dependent responses. In contrast, salicylic acid (SA) biosynthesis and SA‐dependent responses were activated in the T‐DNA insertion mutant . These results show that acts as a conserved negative regulator of plant immunity to pathogens by interfering with JA and SA signalling pathways.