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Evaluation of Implants with Different Macrostructures in Type I Bone—Pre-Clinical Study in Rabbits

机译:I型骨不同宏观结构的植入物评估—家兔的临床前研究

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摘要

The objective of this study was to assess the primary stability and the osseointegration process in implants with different macrostructures (Cylindrical vs. Hybrid Conical) in rabbit tibiae. Twenty-four (24) rabbits were used, divided into 3 experimental periods (2, 4 and 8 weeks) with 8 animals each. Each animal bilaterally received 2 implants from each group in the tibial metaphysis: Cylindrical Implant (CI) and Hybrid Conical Implant (HCI). All implants were assessed for insertion torque. After the experimental periods, one of the implants in each group was submitted to the removal counter-torque test and descriptive histological analysis while the other implant was used for microtomographic and histometric analysis (%Bone-Implant Contact). HCI implants showed higher insertion torque (32.93 ± 10.61 Ncm vs. 27.99 ± 7.80 Ncm) and higher % of bone-implant contact in the 8-week period (79.08 ± 11.31% vs. 59.72 ± 11.29%) than CI implants. However, CI implants showed higher values of removal counter-torque than HCI implants in the 8-week period (91.05 ± 9.32 Ncm vs. 68.62 ± 13.70 Ncm). There were no differences between groups regarding microtomographic data. It can be concluded that HCI implants showed greater insertion torque and bone-implant contact in relation to CI implants in the period of 8 weeks when installed in cortical bone of rabbits.
机译:这项研究的目的是评估兔胫骨中具有不同宏观结构(圆柱形vs.混合锥形)的植入物的主要稳定性和骨整合过程。使用二十四(24)只兔子,分成3个实验期(2、4和8周),每只有8只动物。每只动物从胫骨干physi端的每一组双边接受2种植入物:圆柱形植入物(CI)和混合圆锥形植入物(HCI)。评估所有植入物的插入扭矩。在实验期之后,每组中的一个植入物经受去除抗扭矩测试和描述性组织学分析,而另一植入物被用于显微断层扫描和组织学分析(%骨-植入物接触)。 HCI植入物在8周内显示出比CI植入物更高的插入扭矩(32.93±10.61 Ncm vs. 27.99±7.80 Ncm)和更高的骨-植入物接触百分比(79.08±11.31%vs. 59.72±11.29%)。但是,在8周的时间内,CI植入物显示出比HCI植入物更高的反扭矩去除值(91.05±9.32 Ncm对68.62±13.70 Ncm)。两组之间在显微断层扫描数据方面没有差异。可以得出结论,当将HCI植入物安装在兔的皮质骨中时,与CI植入物相比,在8周内显示出更大的插入扭矩和骨-植入物接触。

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