首页> 美国卫生研究院文献>Journal of Clinical Microbiology >Analytical Evaluation of GeneXpert CT/NG the First Genetic Point-of-Care Assay for Simultaneous Detection of Neisseria gonorrhoeae and Chlamydia trachomatis
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Analytical Evaluation of GeneXpert CT/NG the First Genetic Point-of-Care Assay for Simultaneous Detection of Neisseria gonorrhoeae and Chlamydia trachomatis

机译:同时检测淋病奈瑟氏球菌和沙眼衣原体的第一个遗传基因检测点GeneXpert CT / NG的分析评价

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摘要

GeneXpert CT/NG was evaluated with 372 characterized bacterial strains. Sensitivity of 10 genome copies/reaction was obtained for both agents. Four Neisseria mucosa and two Neisseria subflava isolates were positive for one of two gonococcal targets; however, the assay flagged all as negative. The assay was analytically highly sensitive and specific.
机译:对GeneXpert CT / NG用372株特征性细菌菌株进行了评估。两种试剂均获得10个基因组拷贝/反应的敏感性。四个淋病奈瑟菌粘膜和两个分离的奈瑟菌亚膜分离物对两个淋球菌靶标之一呈阳性反应。但是,该分析将所有标记为阴性。该测定法在分析上具有高度敏感性和特异性。

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