Plasminogen activator inhibitor-2(PAI-2) overexpression supportsbladder cancer developmentin PAI-1 knockout mice in N-butyl-N-(4-hydroxybutyl)-nitrosamine- induced bladdercancer mouse model

摘要

BBN-induced bladder tumorigenesis model. PAI-1 mRNA expression in bladder tissues in WT mice (n = 5 per each time point;  a). PAI-1 protein levels in urine collected from WT mice (n = 5 per each time point;  b). PAI-1 protein levels in plasma collected from WT mice (n = 5 at week 20;  c). Bars represent SD