Nrdp1 increases neuron apoptosis via downregulation of Bruce following intracerebral haemorrhage

摘要

Erythrocyte lysates induces Nrdp1 expression in neurons. Neuron was isolated from the cerebral cortex of newborn mice, and subjected to erythrocyte lysis treatment for 0 or 24 h. The Nrdp1 mRNA levels after erythrocyte lysis treatment was determined by real time RT-PCR. The Nrdp1 protein levels after erythrocyte lysis treatment was determined by western blot analysis. Experiments performed in triplicate showed consistent results. Data are presented as the mean ± SD of three independent experiments. *