Clinical characteristics of insulin resistance syndromes: A nationwide survey in Japan

摘要

Insulin resistance syndrome (IRS) of type A or B is triggered by gene abnormalities of or autoantibodies to the insulin receptor, respectively. Rabson–Mendenhall/Donohue syndrome is also caused by defects of the insulin receptor gene ( ), but is more serious than type A IRS. Here, we carried out a nationwide survey of these syndromes in Japan.