Low CSF/serum ratio of free T4 is associated with decreased quality of life in mild hypothyroidism – A pilot study

著录项

• 期刊名称 Journal of Clinical Translational Endocrinology
• 作者

  Anders Funkquist; Anders Bengtsson; P.M. Johansson; Johan Svensson; Per Bjellerup; Kaj Blennow; Birger Wandt; Stefan Sjöberg;

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• 作者单位

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• 年(卷),期 2020(19),-1
• 年度 2020
• 页码 -1
• 总页数 6
• 原文格式 PDF
• 正文语种
• 中图分类 基础医学;
• 关键词

  s-; serum; CSF; cerebrospinal fluid; HYP; hypothyroid subjects in our study; CON; healthy control group in our study; PH; primary hypothyroidism in general; f-T3 and f-T4; free unbound thyroid hormone; T3; triiodothyronine; T4; thyroxine; TSH; thyroid stimulating hormone; TPO; thyroid peroxidase antibody; Hb; hemoglobulin; CRP; C reactive protein; BBB; blood brain barrier; M; mean value; NS; non-significant; Md; median value; Q1; first quartile; Q3; third quartile; BSA; body surface area; MCT8; monocarboxylate transporter 8; AHDS; Allan-Herndon-Dudley syndrome; OATP1C1; organic anion transporter polypeptide 1C1; DIO2; type II iodothyronine deiodinase-enzyme; QoL; quality of life; MADRS; Montgomery Asberg Depression Rating Scale; GHLS; General Health Likert Scale;

  机译：s-;血清;脑脊液;脑脊液;HYP;本研究中的甲状腺功能减退受试者;CON;我们研究中的健康对照组;PH;原发性甲状腺功能减退;f-T3和f-T4;游离的未结合甲状腺激素;T3;三碘甲状腺素;T4;甲状腺素;TSH;促甲状腺激素;TPO;甲状腺过氧化物酶抗体;血红蛋白CRP;C反应蛋白;BBB;血脑屏障;M;平均值NS;不重要;Md;中值;Q1;第一个四分位数;Q3;第三四分位数;牛血清白蛋白;体表面积;MCT8;单羧酸盐转运蛋白8;AHDS;艾伦-汉顿-达德利综合征OATP1C1;有机阴离子转运蛋白多肽1C1;DIO2;II型碘甲状腺素脱碘酶;生活质量MADRS;蒙哥马利·阿斯伯格抑郁量表;GHLS;一般健康李克特量表;