首页> 美国卫生研究院文献>Journal of the American Association for Laboratory Animal Science : JAALAS >Refinements of Equipment and Methodology to Reduce Risk during Pole-guided Chair Transfer of Nonhuman Primates
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Refinements of Equipment and Methodology to Reduce Risk during Pole-guided Chair Transfer of Nonhuman Primates

机译:改进设备和方法以降低非人类灵长类动物在极引导下转移椅子的风险

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摘要

Neurophysiologic studies of NHP commonly involve their transfer from a housing enclosure to a laboratory by using a mobile chair. This transfer should be performed in a manner that is safe and minimizes stress for both animal and handler. The risk of harm associated with attempting to transfer these animals is increased when they are mature and naïve. We have modified previous chair designs and transfer methodologies to reduce this risk by maintaining a constant barrier between NHP and handler while providing control to the handler to facilitate chairing. Chair modifications were built inhouse, and a commercial, hydraulic lift table was used to dock the primate chair to home cages of different heights. The docking chair method was used with 8 adult, male rhesus macaques. A graduate student transferred the animals without complications. These modifications did not compromise existing features of the chair, they did not require training time in addition to that for the standard chairing method in our facility, and they improved safety. These refinements to a commonly used chair and transfer methodology support rapid habituation, safe transfer and reduced stress for both animal and handler. The refinements we describe mitigate the potential risk of harm during NHP transfers and thus advance animal welfare.
机译:NHP的神经生理学研究通常涉及通过使用移动椅将它们从房屋外壳转移到实验室。这种转移应以安全的方式进行,并尽量减少对动物和处理者的压力。当它们成熟幼稚时,与试图转移这些动物有关的伤害风险就会增加。我们已经修改了以前的椅子设计和转移方法,以通过在NHP和操作人员之间保持恒定的障碍来降低这种风险,同时向操作人员提供控制以促进主持。椅子是在内部建造的,然后使用商用液压升降桌将灵长类动物椅子停靠在不同高度的家用笼子中。对接椅方法用于8只成年雄性恒河猴。一位研究生转移了动物而没有并发症。这些修改并没有损害椅子的现有功能,除了我们工厂的标准椅子方法外,它们不需要培训时间,并且提高了安全性。对常用椅子和转移方法的这些改进支持快速适应习惯,安全转移并减轻了动物和操作者的压力。我们描述的改进措施减轻了NHP转移过程中潜在的伤害风险,从而提高了动物福利。

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