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Neuregulin-1 Protects Neuronal Cells Against Damage due to CoCl2-Induced Hypoxia by Suppressing Hypoxia-Inducible Factor-1α and P53 in SH-SY5Y Cells

机译：Neuregulin-1通过抑制SH-SY5Y细胞中的缺氧诱导因子-1α和P53保护神经元细胞免受CoCl2诱导的缺氧引起的损害。

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Hypoxia-mediated neurotoxicity contributes to various neurodegenerative disorders, including Alzheimer disease. Neuregulin-1 (NRG1) plays an important role in the development and plasticity of the brain. The aim of the present study was to investigate the neuroprotective effect and the regulating hypoxic inducible factor of NRG1 in cobalt chloride (CoCl ) induced hypoxia.

机译：缺氧介导的神经毒性导致多种神经退行性疾病，包括阿尔茨海默氏病。 Neuregulin-1（NRG1）在大脑的发育和可塑性中起重要作用。本研究的目的是研究NRG1在氯化钴（CoCl）诱导的缺氧中的神经保护作用和调节缺氧诱导因子。

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期刊名称 International Neurourology Journal
作者
Seung-Yeon Yoo; Ji-Young Yoo; Han-Byeol Kim; Tai-Kyoung Baik; Jun-Ho Lee; Ran-Sook Woo;
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作者单位

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年(卷),期 2019(23),Suppl 2
年度 2019
页码 -1
总页数 8
原文格式 PDF
正文语种
中图分类神经科学;
关键词
Neuregulin-1; Hypoxia; CoCl;

机译：Neuregulin-1;缺氧;CoCl;

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1. Hypoxia-Inducible Factor-1α Protects Cervical Carcinoma Cells from Apoptosis Induced by Radiation via Modulation of Vascular Endothelial Growth Factor and p53 under Hypoxia [J] . Zhichao Fu, Dongsheng Chen, Huihua Cheng, Medical science monitor : . 2015,第1期

机译：缺氧诱导因子-1α通过低氧诱导的血管内皮生长因子和p53的调节保护宫颈癌细胞免于辐射诱导的凋亡。
2. Hypoxia promotes apoptosis of neuronal cells through hypoxia-inducible factor-1 alpha-microRNA-204-B-cell lymphoma-2 pathway [J] . Wang Xiuwen, Li Ji, Wu Dongjin, Experimental Biology and Medicine: Journal of the Society for Experimental Biology and Medicine . 2016,第2期

机译：缺氧通过缺氧诱导因子1α-microRNA-204-B细胞淋巴瘤2通路促进神经元细胞凋亡
3. Hypoxia-inducible factor-1 alpha upregulates tyrosine hydroxylase and dopamine transporter by nuclear receptor ERR gamma in SH-SY5Y cells [J] . Lim Juhee, Kim Hyo-In, Bang Yeojin, Neuroreport . 2015,第6期

机译：低氧诱导因子-1α通过SH-SY5Y细胞核受体ERRγ上调酪氨酸羟化酶和多巴胺转运蛋白
4. Therapeutic Silencing of Hypoxia-Inducible Factor-1α Using Mixed Micelle Particles Inhibits Prostate Cancer Cell Growth under Hypoxia [C] . Xi-Qiu Liu, Meng-Hua Xiong, Jun Wang World biomaterials congress . 2012

机译：混合胶束粒子对缺氧诱导因子-1α的治疗沉默抑制缺氧条件下前列腺癌细胞的生长
5. Physical Activity Optimizes Circuit-Specific Cellular Metabolism in Neuroplasticity: A Role for Hypoxia-Inducible Factor-1 and its Downstream Targets [D] . Halliday, Matthew Ryan. 2019

机译：物理活性优化神经塑性中的电路特异性细胞代谢：缺氧诱导因子-1的作用及其下游靶标
6. Hypoxia-Inducible Factor-1α Protects Cervical Carcinoma Cells from Apoptosis Induced by Radiation via Modulation of Vascular Endothelial Growth Factor and p53 under Hypoxia [O] . Zhichao Fu, Dongsheng Chen, Huihua Cheng, 2015

机译：缺氧诱导因子-1α通过调节缺氧诱导的血管内皮生长因子和p53的辐射诱导宫颈癌细胞凋亡。
7. Hypoxia-Inducible Factor-1α Protects Cervical Carcinoma Cells from Apoptosis Induced by Radiation via Modulation of Vascular Endothelial Growth Factor and p53 under Hypoxia [O] . Fengmei Wang 2015

机译：缺氧诱导因子-1α通过调节血管内皮生长因子和缺氧下P53的辐射辐射诱导的凋亡诱导的胚性癌细胞

Neuregulin-1 Protects Neuronal Cells Against Damage due to CoCl2-Induced Hypoxia by Suppressing Hypoxia-Inducible Factor-1α and P53 in SH-SY5Y Cells

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