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Hypoxia-Inducible Factor-1α Protects Cervical Carcinoma Cells from Apoptosis Induced by Radiation via Modulation of Vascular Endothelial Growth Factor and p53 under Hypoxia

机译：缺氧诱导因子-1α通过调节缺氧诱导的血管内皮生长因子和p53的辐射诱导宫颈癌细胞凋亡。

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摘要

BackgroundThe aim of the study was to assess the role of irradiation in the expression of HIF-1α, VEGF, and P53 in human cervical carcinoma cells under a simulated hypoxia environment.

机译：背景研究的目的是评估在模拟缺氧环境下辐射在人宫颈癌细胞中HIF-1α，VEGF和P53表达的作用。

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期刊名称 Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
作者
Zhichao Fu; Dongsheng Chen; Huihua Cheng; Fengmei Wang;
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作者单位

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年(卷),期 2015(21),-1
年度 2015
页码 318–325
总页数 8
原文格式 PDF
正文语种
中图分类
关键词
Abnormalities Radiation-Induced; Apoptosis; Genes p53; Vascular Endothelial Growth Factor Endocrine-Gland-Derived;

机译：辐射引起的异常;细胞凋亡;基因;p53;血管内皮生长因子;内分泌腺衍生;

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专利

1. Hypoxia-Inducible Factor-1α Protects Cervical Carcinoma Cells from Apoptosis Induced by Radiation via Modulation of Vascular Endothelial Growth Factor and p53 under Hypoxia [J] . Zhichao Fu, Dongsheng Chen, Huihua Cheng, Medical science monitor : . 2015 ,第1期

机译：缺氧诱导因子-1α通过低氧诱导的血管内皮生长因子和p53的调节保护宫颈癌细胞免于辐射诱导的凋亡。
2. Fasudil-induced hypoxia-inducible factor-1{alpha} degradation disrupts a hypoxia-driven vascular endothelial growth factor autocrine mechanism in endothelial cells. [J] . Takata K, Morishige K, Takahashi T, Molecular cancer therapeutics . 2008 ,第6期

机译：法舒地尔诱导的缺氧诱导因子-1 {α}降解破坏了内皮细胞中缺氧驱动的血管内皮生长因子自分泌机制。
3. Effects of the hypoxia-inducible factor-1 inhibitor echinomycin on vascular endothelial growth factor production and apoptosis in human ectopic endometriotic stromal cells [J] . Tsuzuki Tomoko, Okada Hidetaka, Shindoh Hisayuu, Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology . 2016 ,第1a6期

机译：缺氧诱导因子-1抑制剂棘霉素对人异位子宫内膜异位基质细胞血管内皮生长因子的产生和凋亡的影响
4. Therapeutic Silencing of Hypoxia-Inducible Factor-1α Using Mixed Micelle Particles Inhibits Prostate Cancer Cell Growth under Hypoxia [C] . Xi-Qiu Liu, Meng-Hua Xiong, Jun Wang World biomaterials congress . 2012

机译：混合胶束粒子对缺氧诱导因子-1α的治疗沉默抑制缺氧条件下前列腺癌细胞的生长
5. The role of protein kinases in hypoxia-inducible factor 1-alpha induced erythropoietin gene expression in hepatocellular carcinoma (Hep3B) cells. [D] . Gutierrez Figueroa, Yanira. 2004

机译：蛋白激酶在肝细胞癌（Hep3B）细胞中的缺氧诱导因子1-α诱导的促红细胞生成素基因表达中的作用。
6. Effects of Tetrahydrocurcumin on Hypoxia-Inducible Factor-1α and Vascular Endothelial Growth Factor Expression in Cervical Cancer Cell-Induced Angiogenesis in Nude Mice [O] . Bhornprom Yoysungnoen, Parvapan Bhattarakosol, Suthiluk Patumraj, -1

机译：四氢姜黄素对宫颈癌细胞诱导的缺氧小鼠缺氧诱导因子-1α和血管内皮生长因子表达的影响
7. Hypoxia-Inducible Factor-1α Protects Cervical Carcinoma Cells from Apoptosis Induced by Radiation via Modulation of Vascular Endothelial Growth Factor and p53 under Hypoxia [O] . Fengmei Wang 2015

机译：缺氧诱导因子-1α通过调节血管内皮生长因子和缺氧下P53的辐射辐射诱导的凋亡诱导的胚性癌细胞

Hypoxia-Inducible Factor-1α Protects Cervical Carcinoma Cells from Apoptosis Induced by Radiation via Modulation of Vascular Endothelial Growth Factor and p53 under Hypoxia

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