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Donor-derived fatal hyperinfection strongyloidiasis in renal transplant recipient

机译:肾移植受者的供体源性致命性过度感染性类圆线虫病

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摘要

is a nematode, endemic in tropical and subtropical areas. Strongyloidiasis has been reported in recipients of hematopoietic stem cells, kidney, liver, heart, intestine, and pancreas, eventually presenting as disseminated strongyloidiasis and hyperinfection syndrome (SHS) which is associated with high mortality. We report one case of a recent renal transplant recipient, who presented with gastrointestinal and respiratory symptoms, evolving into shock. The identification of in the bronchoalveolar lavage (BAL) lead us to the diagnosis of SHS. Treatment with subcutaneous ivermectin was started, however the patient did not survive. Retrospective serum donor analysis allowed us to identify the donor as the source of infection.
机译:是一种线虫,在热带和亚热带地区特有。据报道,在造血干细胞,肾脏,肝脏,心脏,肠和胰腺的受体中存在类圆线虫病,最终表现为传播性的类圆线虫病和高感染综合征(SHS),与高死亡率相关。我们报告了一个最近的肾移植受者的病例,该患者出现胃肠道和呼吸道症状,发展为休克。支气管肺泡灌洗(BAL)中的鉴定导致我们诊断为SHS。开始使用伊维菌素皮下治疗,但是该患者无法存活。回顾性血清供体分析使我们能够确定供体为感染源。

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