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The Prevalence of Delirium in An Older Acute Surgical Population and Its Effect on Outcome

机译:老年急性手术人群中Deli妄的发生率及其对结局的影响

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摘要

Background: With an ageing population, an increasing number of older adults are admitted for assessment to acute surgical units. Older adults have specific factors that may influence outcomes, one of which is delirium (acute cognitive impairment). Objectives: To establish the prevalence of delirium on admission in an older acute surgical population and its effect on mortality. Secondary outcomes investigated include hospital readmission and length of hospital stay. Method: This observational multi-centre study investigated consecutive patients, ≥65 years, admitted to the acute surgical units of five UK hospitals during an eight-week period. On admission the Confusion Assessment Method (CAM) score was performed to detect delirium. The effect of delirium on important clinical outcomes was investigated using tests of association and logistic regression models. Results: The cohort consisted of 411 patients with a mean age of 77.3 years (SD 8.1). The prevalence of admission delirium was 8.8% (95% CI 6.2–11.9%) and cognitive impairment was 70.3% (95% CI 65.6–74.7%). The delirious group were not more likely to die at 30 or 90 days (OR 1.1, 95% CI 0.2 to 5.1, = 0.67; OR 1.4, 95% CI 0.4 to 4.1. = 0.82) or to be readmitted within 30 days of discharge (OR 0.9, 95% CI 0.4 to 2.2, = 0.89). Length of hospital stay was significantly longer in the delirious group (median 8 vs. 5 days respectively, = 0.009). Conclusion: Admission delirium occurs in just under 10% of older people admitted to acute surgical units, resulting in significantly longer hospital stays.
机译:背景:随着人口的老龄化,越来越多的老年人被允许接受急诊手术室评估。老年人有可能影响预后的特定因素,其中之一就是del妄(急性认知障碍)。目的:建立older妄在老年急性外科手术人群中的患病率及其对死亡率的影响。研究的次要结果包括住院再入院和住院时间。方法:这项多中心观察性研究调查了连续八周内≥65岁,在英国五家医院的急性外科住院的≥65岁的患者。入院时进行混淆评估法(CAM)评分以检测del妄。 association妄对重要临床结局的影响使用联想和逻辑回归模型进行了研究。结果:该队列由411名患者组成,平均年龄为77.3岁(SD 8.1)。入ir妄的患病率为8.8%(95%CI 6.2–11.9%)和认知障碍为70.3%(95%CI 65.6–74.7%)。精神错乱的人群不太可能在30或90天后死亡(OR 1.1,95%CI 0.2至5.1,= 0.67; OR 1.4,95%CI 0.4至4.1。= 0.82)或在出院后30天内重新入院(或0.9,95%CI 0.4至2.2,= 0.89)。精神错乱组的住院时间明显更长(中位数分别为8天和5天,= 0.009)。结论:入院ir妄的发生率低于接受急性外科手术的老年人中的不到10%,从而导致住院时间明显延长。

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