Formulation of HBs antigen in Montanide ISA266 shows superiority to commercial HBsAg vaccine in the induction of humoral immune responses

机译：在Montanide ISA266中配制HBs抗原在诱导体液免疫反应方面优于商业HBsAg疫苗

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摘要

In the present study, a new formulation of HBsAg vaccine was developed and compared with a commercial peer.

机译：在本研究中，开发了一种新的HBsAg疫苗制剂，并与商业同行进行了比较。

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期刊名称 Gastroenterology and Hepatology From Bed to Bench
作者
Mohammad Ali Savoji; Setareh Haghighat; Mina Mirzaee; Bahareh Golkaran; Rayhaneh Mirzaee; Behzad Esfandiari; Mehdi Mahdavi;
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作者单位

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年(卷),期 2019(12),4
年度 2019
页码 -1
总页数 9
原文格式 PDF
正文语种
中图分类肠道病毒与肝炎病毒;肝及胆疾病;肠疾病;
关键词
Adjuvant; Hepatitis B vaccine; Montanide ISA 266; Immune response;

机译：佐剂;乙型肝炎疫苗;Montanide ISA 266;免疫应答;

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专利

1. Recombinant PBP2a of methicillin-resistant S. aureus formulation in Alum and Montanide ISA266 adjuvants induced cellular and humoral immune responses with protection in Balb/C mice [J] . Microbial Pathogenesis . 2020,第期

机译：耐甲氧脲S. aureus制剂的重组PBP2A在Alum和蒙土中的ASA266佐剂在Balb / C小鼠中诱导细胞和体液免疫应答
2. A human-derived protein SBP (HBsAg-binding protein) can bind to hepatitis B virus surface antigen (HBsAg) and enhance the immune response to hepatitis B virus (HBV) vaccine. [J] . Chongwen Zhang, Li Gong, Yuanyuan Chen, Molecular Immunology . 2013,第1a2期

机译：人衍生的蛋白质SBP（HBsAg结合蛋白）可以与乙型肝炎病毒表面抗原（HBsAg）结合，并增强对乙型肝炎病毒（HBV）疫苗的免疫应答。
3. A human-derived protein SBP (HBsAg-binding protein) can bind to hepatitis B virus surface antigen (HBsAg) and enhance the immune response to hepatitis B virus (HBV) vaccine. [J] . Chongwen Zhang, Li Gong, Yuanyuan Chen, Molecular Immunology . 2012,第1a2期

机译：人源蛋白SBP（HBsAg结合蛋白）可以与乙型肝炎病毒表面抗原（HBsAg）结合并增强对乙型肝炎病毒（HBV）疫苗的免疫反应。
4. Combining hepatitis B surface antigen (HBsAg) with anthrax (rPA) for a single oral vaccine [C] . Vishal Bhargava, Saurabh Bhargava, Gomed Agarwal World biomaterials congress . 2016

机译：结合乙型肝炎表面抗原（HBsAg）和炭疽（rPA）进行单一口服疫苗
5. The TH2 bias in CNS immune privilege: Induction of humoral, cellular, and cytokine immune responses to soluble protein antigen administered into the cerebrospinal fluid of mice with normal blood brain barrier permeability. [D] . Park, Joel Thomas, II. 2003

机译：在中枢神经系统免疫特权中的TH2偏倚：诱导对可溶性蛋白抗原的体液，细胞和细胞因子免疫反应，这些抗原被注入具有正常血脑屏障通透性的小鼠的脑脊液中。
6. Minimally invasive and surface electroporation delivery of DNA vaccines for the induction of robust humoral immune responses against HIV antigens [O] . NY Sardesai, AS Khan, J McCoy, 2012

机译：DNA疫苗的微创和表面电穿孔递送可诱导针对HIV抗原的强大体液免疫反应
7. Minimally invasive and surface electroporation delivery of DNA vaccines for the induction of robust humoral immune responses against HIV antigens [O] . Sardesai NY, Khan AS, McCoy J, 2012

机译：DNA疫苗的微创和表面电穿孔递送，可诱导针对HIV抗原的强大体液免疫反应
8. Mechanism Underlying T Cell Help for Induction of an Antigen- Specific In Vivo Humoral Immune Response to Intact Streptococcus pneumoniae Is Dependent on the Type of Antigen [R] . Wu, Z., Shen, Y., Khan, A. Q., 2002

机译：T细胞帮助诱导针对完整肺炎链球菌的抗原特异性体内免疫应答的机制取决于抗原类型

Formulation of HBs antigen in Montanide ISA266 shows superiority to commercial HBsAg vaccine in the induction of humoral immune responses

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