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Associations of self-reported stair climbing with all-cause and cardiovascular mortality: The Harvard Alumni Health Study

机译:自我报告的爬楼梯与全因和心血管疾病死亡率的关联:哈佛校友健康研究

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摘要

To evaluate the association between numbers of floors climbed (per week) and all-cause and cardiovascular (CVD) mortality in men. A prospective study was conducted in 8874 men (Median [interquartile range] age: 65 years [60–71.6 years]) from the Harvard Alumni Health Study. Participants reported the number of floors habitually climbed, physical activity in their leisure time, other health related behaviours and any physician diagnosed disease in 1988. Men were followed for mortality through December 2008. Multivariate Cox hazard models to examine the association between weekly number of floors climbed and all-cause and CVD mortality adjusted for participation in total physical activity and other confounders.During a median follow-up of 12.4 years, 4063 men died (1195 from CVD). After adjusting for confounders (age, walking, sports/recreation, body mass index, alcohol intake, and smoking, diagnoses of hypertension or diabetes or high cholesterol) number of stairs habitually climbed was inversely associated with all-cause mortality (p trend <0.001). Compared with the group who climbed <10 floors/week, the hazard ratio (HR) for the ≥35 floors/week group was 0.84 95% confidence interval (CI) (0.78–0.91). In contrast, we found no evidence for an association between stair climbing and CVD mortality risk (p trend = 0.38), in the ≥35 floors/week group: HR = 0.94 95%CI (0.81–1.09). In this cohort of older men, stair climbing was associated with a lower risk of mortality from any causes. Further insights may be gained from future observational studies utilizing emerging pattern recognition of stair climbing from objective measurements of physical activity.
机译:为了评估(每周)攀爬楼层数与男性全因和心血管(CVD)死亡率之间的关联。一项来自哈佛校友健康研究的8874名男性(四分位间距的中间年龄:65岁[60-71.6岁])进行了一项前瞻性研究。参与者于1988年报告了惯常爬升的楼层数,休闲时间的体力活动,其他与健康有关的行为以及任何医生诊断出的疾病。随访了直到2008年12月的男性死亡率。多变量Cox风险模型用于检验每周楼层数之间的关系上升,并根据参与总体体育活动和其他混杂因素调整了全因和CVD死亡率。在中位随访时间12.4年中,有4063例男性死亡(1195例因CVD死亡)。在调整混杂因素(年龄,步行,运动/娱乐,体重指数,酒精摄入和吸烟,诊断出高血压或糖尿病或高胆固醇)后,习惯爬楼梯的次数与全因死亡率成反比(p趋势<0.001 )。与每周攀登<10层以下的组相比,≥35层/周的组的危险比(HR)为0.84 95%置信区间(CI)(0.78–0.91)。相反,在≥35楼/周组中,我们没有发现爬楼梯与CVD死亡风险之间存在关联的证据(p趋势= 0.38):HR = 0.94 95%CI(0.81-1.09)。在这一年龄较大的队列中,爬楼梯与因任何原因导致的死亡风险较低有关。未来的观察性研究可能会从对身体活动的客观测量中利用新兴的爬楼梯模式识别来获得更多的见解。

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