15th National Breast Diseases Congress

摘要

Idiopathic granulomatous mastitis (IGM) is a rare benign chronic inflammatory breast disease. Although the etiology is unknown, some conditions such as autoimmune diseases, infectious causes, hormonal disorders and pregnancy are blamed. Cellular or humoral immune system disorders may be seen in patients. Cytokines are proteins involved in immune function, inflammation and wound healing. Interleukin (IL) −4; is released from T cells and mast cells and is the most important stimulant of immunoglobulin E production. IL-8; is released from macrophages and is responsible for chemotaxis. IL-10 acts as an inhibitor in the control of the immune response. IL-17 plays a proinflammatory role. TNF-α is the most important mediator of acute inflammatory response. The aim of this study was to evaluate the levels of IL-4, IL-8, IL-10, IL-17 and TNF-alpha in patients diagnosed with IGM.