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Comparing The Efficacy Of An Anti-Human VEGF-A Neutralizing Antibody Versus Bevacizumab On A Laser-Induced Choroidal Neovascularization (CNV) Rhesus Monkey Model

机译：比较抗人VEGF-A中和抗体与贝伐单抗在激光诱导的脉络膜新血管形成（CNV）恒河猴模型上的功效

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摘要

To evaluate the efficacy of a therapy on improving characteristics of laser-induced choroidal neovascularization (CNV) via single intravitreal injection of a humanized anti-human VEGF monoclonal antibody (PRO-169) versus bevacizumab in a rhesus monkey model.

机译：为了评估在恒河猴模型中通过单次玻璃体内注射人源化抗人VEGF单克隆抗体（PRO-169）与贝伐单抗来改善激光诱导的脉络膜新生血管（CNV）特性的治疗效果。

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期刊名称 Drug Design Development and Therapy
作者
Oscar Olvera-Montaño; Leopoldo Baiza-Duran; Juan D Quintana-Hau; Mayra G Quiñonez-Alvarado; Wen Zeng; Li Gong; Patricia Muñoz-Villegas;
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年(卷),期 2019(13),-1
年度 2019
页码 -1
总页数 9
原文格式 PDF
正文语种
中图分类药学;药物化学;
关键词
age-related macular degeneration; monoclonal antibodies; fundus fluorescein angiography; optical coherence tomography;

机译：年龄相关性黄斑变性;单克隆抗体;眼底荧光素血管造影;光学相干断层扫描;

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1. Comparing The Efficacy Of An Anti-Human VEGF-A Neutralizing Antibody Versus Bevacizumab On A Laser-Induced Choroidal Neovascularization (CNV) Rhesus Monkey Model [J] . Oscar Olvera-Monta?o, Leopoldo Baiza-Duran, Juan D Quintana-Hau, Drug Design, Development and Therapy . 2019,第1期

机译：比较抗人VEGF-A中和抗体对激光诱导的脉络膜新生血管（CNV）恒河猴模型的疗效
2. Recombinant humanized anti-vascular endothelial growth factor monoclonal antibody efficiently suppresses laser-induced choroidal neovascularization in rhesus monkeys [J] . Wan-Wan Ji, Dong-An Yu, Peng Yang, European journal of pharmaceutical sciences . 2017,第期

机译：重组人源化抗血管内皮生长因子单克隆抗体有效地抑制了恒河猴中的激光诱导的脉络膜新生血管形成
3. Vascular Endothelial Growth Factor Receptor 2 Antibody, BC001, Attenuates Laser-Induced Choroidal Neovascularization in Rhesus Monkeys (Macaca mulatta) [J] . Zhao Tao, Zhang Jie, Zhang Yanyan, Journal of ocular pharmacology and therapeutics: The official journal of the Association for Ocular Pharmacology and Therapeutics . 2015,第10期

机译：血管内皮生长因子受体2抗体，BC001，可减轻恒河猴（猕猴）中激光诱导的脉络膜新生血管形成
4. A model for choroidal neovascularization (CNV) and gene therapy for age-related macular degeneration (AMD). [D] . Wang, Fei. 2001

机译：脉络膜新生血管（CNV）和年龄相关性黄斑变性（AMD）基因治疗的模型。
5. Intravitreal Tanibirumab a Fully Human Monoclonal Antibody Against Vascular Endothelial Growth Factor Receptor 2 Partially Suppresses and Regresses Laser-Induced Choroidal Neovascularization in a Rat Model [O] . Jaeryung Kim, Tae Eun Kim, Ju-A Kim, -1

机译：玻璃体内Tanibirumab一种针对血管内皮生长因子受体2的完整人类单克隆抗体部分抑制和退行大鼠模型中的激光诱导的脉络膜新生血管形成
6. >Comparing The Efficacy Of An Anti-Human VEGF-A Neutralizing Antibody Versus Bevacizumab On A Laser-Induced Choroidal Neovascularization (CNV) Rhesus Monkey Model [O] . Oscar Olvera-Montaño, Leopoldo Baiza-Duran, Juan D Quintana-Hau, 2019

机译：比较抗人VEGF-A中和抗体对激光诱导的脉络膜新生血管（CNV）恒河猴模型的效果

Comparing The Efficacy Of An Anti-Human VEGF-A Neutralizing Antibody Versus Bevacizumab On A Laser-Induced Choroidal Neovascularization (CNV) Rhesus Monkey Model

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