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GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways

机译：GE11肽缀合的硒纳米粒子用于EGFR靶向的冬凌草甲素递送可通过抑制EGFR介导的PI3K / AKT和Ras / Raf / MEK / ERK途径来实现增强的抗癌功效

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期刊名称 Drug Delivery
作者
Jiang Pi; Jinhuan Jiang; Huaihong Cai; Fen Yang; Hua Jin; Peihui Yang; Jiye Cai; Zheng W. Chen;
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作者单位

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年(卷),期 2017(24),1
年度 2017
页码 -1
总页数 16
原文格式 PDF
正文语种
中图分类药学;
关键词
Selenium nanoparticles; GE11 peptide; oridonin; delivery; EGFR targeting;

机译：硒纳米颗粒;GE11肽;降钙素原;递质;EGFR靶向;

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专利

1. GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways [J] . Jiang Pi, Jinhuan Jiang, Huaihong Cai, Drug delivery. . 2017,第InaProgress期

机译：GE11肽缀合的硒纳米粒子，用于EGFR靶向的冬凌草甲素递送，可通过抑制EGFR介导的PI3K / AKT和Ras / Raf / MEK / ERK途径来增强抗癌功效
2. Polygonatum odoratum lectin induces apoptosis and autophagy via targeting EGFR-mediated Ras-Raf-MEK-ERK pathway in human MCF-7 breast cancer cells [J] . OuyangL., ChenY., WangX.-Y., Phytomedicine : . 2014,第12期

机译：玉竹凝集素通过靶向人MCF-7乳腺癌细胞中EGFR介导的Ras-Raf-MEK-ERK途径诱导凋亡和自噬
3. Goji Berry Fruit Extracts Suppress Proliferation of Triple-Negative Breast Cancer Cells by Inhibiting EGFR-Mediated ERK/MAPK and PI3K/Akt Signaling Pathways [J] . Cumaoglu Ahmet, Bekci Hatice, Ozturk Ebru, Natural product communications . 2018,第6期

机译：Goji Berry Fruit通过抑制EGFR介导的ERK / MAPK和PI3K / AKT信号通路来抑制三阴性乳腺癌细胞的增殖
4. SINGLE CHAIN VARIABLE FRAGMENT CD7 ANTIBODY CONJUGATED PLGA/HDAC INHIBITOR IMMUNO-NANOPARTICLES: DEVELOPING HUMAN T CELL-SPECIFIC NANO-TECHNOLOGY FOR DELIVERY OF THERAPEUTIC DRUGS TARGETING LATENT HIV [C] . Sunmi Choi, Jangwook Lee, Priti Kumar, Symposium on innovative polymers for controlled delivery: Abstract book. . 2010

机译：单链可变片段CD7抗体共轭PLGA / HDAC抑制剂免疫纳米颗粒：开发人类T细胞特异性纳米技术以递送靶向药物的新型治疗性药物
5. Targeting the MEK5, MEK1/2, and/or Pi3k Pathways Reverses Epithelial to Mesenchymal Transition and Enhances Chemotherapeutic Sensitivity in Breast and Brain Cancers with a Mesenchymal Phenotype [D] . Bhatt, Akshita B. 2021

机译：靶向MEK5，MEK1 / 2和/或PI3K途径将上皮细胞转型的上皮性反转，并通过间充质表型提高乳腺癌和脑癌中的化疗敏感性
6. P-021Tanshinone IIA can inhibit human pancreatic carcinoma BxPC3 cells through decreasing the protein expressions of IGFR EGFR VEGFR and blocking both Ras/Raf/MEK/ERK and Ras/PI3K/AKT/mTOR pathway in vitro and in vivo [O] . C.C. Su -1

机译：P-021丹参酮IIA可以通过降低IGFREGFRVEGFR的蛋白质表达并阻断Ras / Raf / MEK / ERK和Ras / PI3K / AKT / mTOR通路来抑制人胰腺癌BxPC3细胞
7. GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways [O] . Jiang Pi, Jinhuan Jiang, Huaihong Cai, 2017

机译：GE11肽缀合的硒纳米粒子用于EGFR靶向奥凡啉递送，通过抑制EGFR介导的PI3K / AKT和RAS / RAF / MEK / ERK途径来实现增强的抗癌效果

GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways

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