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Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics

机译：通过体外早期毒性和脱靶责任分析中的高通量收集数据以快速确定新型胸腺肽组学的局限性

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期刊名称 Data in Brief
作者
Massimiliano Runfola; Simona Sestito; Sheraz Gul; Grazia Chiellini; Simona Rapposelli;
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作者单位

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年(卷),期 2020(29),-1
年度 2020
页码 -1
总页数 10
原文格式 PDF
正文语种
中图分类
关键词
Triiodothyronine; Thyronamine; TRβ selective agonist; Fatty-liver disorder; Liver regeneration; ADME-Tox profile; Off-target liability; Screening;

机译：三碘甲状腺素;胸腺嘧啶;TRβ选择性激动剂;脂肪肝疾病;肝再生;ADME-Tox谱;脱靶责任;筛选;
入库时间 2022-08-21 11:37:53

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1. Collecting data through high throughput in?vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics [J] . Massimiliano Runfola, Simona Sestito, Sheraz Gul, Data in Brief . 2020,第2期

机译：通过高通量收集数据体外：斜体>早期毒性和脱靶责任测定以迅速识别新型晶体的局限性
2. Big data in chemical toxicity research: The use of high-throughput screening assays to identify potential toxicants [J] . ZhuH., ZhangJ., KimM.T., Chemical research in toxicology . 2014,第10期

机译：化学毒性研究中的大数据：使用高通量筛选测定法来识别潜在的毒性物质
3. Computational prediction of off-target related safety liabilities of molecules: Cardiotoxicity, hepatotoxicity and reproductive toxicity [J] . Schmidt Friedemann, Amberg Alexander, Mulliner Denis, Toxicology Letters: An International Journal Providing a Forum for Original and Pertinent Contributions in Toxicology Research . 2014,第Null期

机译：分子脱靶相关安全性责任的计算预测：心脏毒性，肝毒性和生殖毒性
4. High throughput genotoxicity assay of nanomaterials with single cell HaloChip assay [C] . Yong Qiao, Liyuan (Linda) Ma Society for Biomaterials annual meeting and exposition . 2015

机译：单细胞HaloChip分析法对纳米材料的高通量遗传毒性分析
5. Development of in vitro toxicity assays with a rainbow trout gill cell line and their use in determining the cytotoxicity and photocytotoxicity of polycyclic aromatic hydrocarbons individually and in a complex mixture [D] . Schirmer, Kristin 1997

机译：虹鳟鱼g细胞系体外毒性试验的发展及其在确定单个或复杂混合物中多环芳烃的细胞毒性和光细胞毒性中的用途
6. Big Data in Chemical ToxicityResearch: The Use ofHigh-Throughput Screening Assays To Identify Potential Toxicants [O] . Hao Zhu, *, Jun Zhang, -1

机译：化学毒性大数据研究：使用高通量筛查方法可识别潜在的有毒物质
7. Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics [O] . Massimiliano Runfola, Simona Sestito, Sheraz Gul, 2020

机译：通过高通量的体外早期毒性和脱靶责任测定来收集数据，以迅速识别新型晶体的局限性
8. Results from Two In Vitro Genotoxicity Assays (Reverse Mutation Assay and Mouse Lymphoma Assay) with Substituted pyrazole (star 2). [R] . 2011

机译：两种体外基因毒性测定（反向突变测定和小鼠淋巴瘤测定）与取代的吡唑（星形2）的结果。

Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics

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