Investigating cone photoreceptor development using patient-derived NRL null retinal organoids

摘要

– Confocal images of d100 (stage 2) organoids from a WT line ( – ) or three individual clonal lines of the L75Pfs mutant ( – ) showing photoreceptors immunostained for RCVN ( , , , ), CRX ( , , , ), or NRL ( , , , ). , , , : nuclei (blue); , , merge in : merge). Scale bars = 50 μm.