Cardiovascular prevention: Frontiers in lipid guidelines

摘要

Cardiovascular disease (CVD) remains one of the principal causes of morbidity and mortality in the world. International guidelines are being updated to take into account new evidence and improved health economics as drug patents expire. Recent studies have investigated the best lipid fractions to predict CVD, suggested additional CVD risk factors and a potential role for novel biomarkers while big data approaches have allowed improvements to be made to CVD risk calculators. The increasing availability of next generation sequencing is allowing systematic efforts to be made to detect monogenic familial hypercholesterolaemia.