Exploring neuroimaging-genetic co-alteration features of auditory verbal hallucinations in different subjects for the establishment of a predictive model

摘要

Auditory verbal hallucination (AVH) is defined as the hearing of voices in the absence of any external auditory stimulus. Most AVH content is related to the experiencer, and these events usually cause serious distress. AVHs can occur in patients with a broad range of mental disorders and neurological diseases, such as schizophrenia, bipolar disorder (BP), major depressive disorder (MDD), post-traumatic stress disorder (PTSD), borderline personality disorder (BPD), and in healthy individuals. They are most prevalent in schizophrenic patients, affecting more than 70% of this population. Beyond schizophrenia, up to 46% of patients with BPD, 11.3% to 62.8% of persons with BP, 5.4% to 40.6% of those with MDD, and 4.2% of individuals in the general population experience AVHs.