Cisplatin-induced ototoxicity in organotypic cochlear cultures occurs independent of gap junctional intercellular communication

摘要

Representative confocal images of Cx26 and Cx30 distribution in organotypic cochlear cultures from WT and Cx43 mutant mice denoting the apical (low-), middle (mid-), and basal (high-frequency) regions. Representative confocal images of Cx26 and Cx30 distribution in organotypic cochlear cultures of WT and Cx43 mutant mice. OHC1 outer hair cell row 1, OHC2 outer hair cell row 2, OHC3 outer hair cell row 3, IHC inner hair cell. Cx30 is denoted in green, Cx26 is in red, phalloidin labeling hair cell stereocilia is in white, and Hoechst nuclear stain is in blue. Scale bars = 20 μm.