Deletion of low-density lipoprotein-related receptor 5 inhibits liver Cancer cell proliferation via destabilizing Nucleoporin 37

摘要

Knockdown of LRP5 inhibits the proliferation of HepG2 cells. Representative image of HepG2 cells following siRNA knockdown of LRP5 (three distinct siRNA targeting different segment of LRP5 ORF), LRP6 or β-catenin for 48 h (left).  = 3. Quantification of total cell count. ***  b CCK8 and MTT assays of cell proliferation and cell viability in HepG2 cells following siRNA knockdown of three distinct siRNA targeting LRP5 ORF. **