Images – pT3a clear-cell renal cell carcinoma in a renal allograft managed effectively with open partial nephrectomy

摘要

Primary renal cell carcinoma (RCC) post-kidney transplantation can occur in either the native kidney(s) or renal allograft, although their occurrence is significantly rarer in the latter. Immunosuppressive therapy is known to increase the incidence of various malignancies in patients on these regimens due to their effects on the immune system and their role in anti-cancer immune surveillance. Neoplasms can develop as the result of accidental transplantation from donor with undetected primary cancer, recurrence or undiagnosed metastases, or de novo. As well, these tumors tend to be more aggressive, confer a poor prognosis, and are associated with a higher rate of recurrence than the same tumors in the general population.