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Endemic Carbapenem Resistance Associated with OXA-40 Carbapenemase among Acinetobacter baumannii Isolates from a Hospital in Northern Spain

机译:西班牙北部一家医院鲍曼不动杆菌中与OXA-40碳青霉烯酶相关的地方性碳青霉烯耐药性

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摘要

Eighty-two carbapenem-resistant isolates of Acinetobacter baumannii from a single hospital in Bilbao were typed into two major clusters and several subclusters. Disk synergy tests and PCR indicated the production of a zinc-independent OXA-class carbapenemase. Sequencing identified this enzyme, OXA-40, as a variant of the OXA-24-OXA-25-OXA-26 cluster.
机译:来自毕尔巴鄂一家医院的八十二种耐碳青霉烯类鲍曼不动杆菌的菌株被分为两个主要簇和几个亚类。磁盘协同作用测试和PCR表明产生了锌独立的OXA类碳青霉烯酶。测序鉴定该酶OXA-40为OXA-24-OXA-25-OXA-26簇的变体。

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