Polymorphous low-grade neuroepithelial tumor of the young: case report and review focus on the radiological features and genetic alterations

摘要

The MR images and pathological images of a 14-year-old girl with PLNTY in the left temporal lobe. The MR images and pathological images of a 14-year-old girl with PLNTY in the left temporal lobe. , The tumor (arrow) appeared as clear-marginated cortical mass with slightly hypointensity in T1WI. , The tumor (arrow) showed hyperintensity with “salt and pepper sign” in T2WI. , The tumor (arrow) showed no enhancement after contrast agent injection. (H-E staining,40×), Under microscopy, the tumor, located in the cerebral cortex and superficial white matter, showed an infiltrative growth pattern with adjacent tissue involvement and subpial extension. (H-E staining, 200×), Oligodendrocyte-like-cells (short arrow), astrocytes, and spindle cells with moderate nuclear pleomorphism (arrow heads) and scattered calcifications (arrows) can be seen inside the tumor