Novel immunomodulatory drugs and neo-substrates

机译：新型免疫调节药物和新底物

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

Chemical structure and mechanism of action of IMiDs. Chemical structure of thalidomide, lenalidomide, pomalidomide, CC-122, CC-885 and CC-220. IMiDs (purple rhombuses) bind to CRBN, a substrate receptor of CRL4 E3 ligase, to recruit substrates for ubiquitination and proteasomal degradation. Ub, ubiquitin

机译：IMiDs的化学结构和作用机理。沙利度胺，来那度胺，泊马利度胺，CC-122，CC-885和CC-220的化学结构。 IMiD（紫色菱形）与CRL4 E3连接酶的底物受体CRBN结合，募集底物用于泛素化和蛋白酶体降解。泛素

著录项

期刊名称 Biomarker Research
作者
Shaobing Gao; Shichao Wang; Yongping Song;
展开▼
作者单位

展开▼
年(卷),期 2020(8),-1
年度 2020
页码 -1
总页数 8
原文格式 PDF
正文语种
中图分类生物学;
关键词
Immunomodulatory drugs; CRL4;

机译：免疫调节药物;CRL4;

相似文献

外文文献
中文文献
专利

1. Novel immunomodulatory drugs and neo-substrates [J] . Shaobing Gao, Shichao Wang, Yongping Song Biomarker Research . 2020,第1期

机译：新型免疫调节药物和新基材
2. A Comparative Study of Longitudinal Toxicities of Cytotoxic Drugs, Molecularly Targeted Agents, Immunomodulatory Drugs, and Cancer Vaccines [J] . Hirakawa Akihiro, Sudo Kazuki, Yonemori Kan, Clinical Pharmacology and Therapeutics . 2019,第4期

机译：细胞毒性药物，分子靶向剂，免疫调节药物和癌症疫苗纵向毒性的比较研究
3. Low Beclin-1 expression predicts improved overall survival in patients treated with immunomodulatory drugs for multiple myeloma and identifies autophagy inhibition as a promising potentially druggable new therapeutic target: an analysis from The Austrian Myeloma Registry (AMR) [J] . Willenbacher Wolfgang, Thangavadivel Shanmugapriya, Greil Richard, Leukemia and lymphoma . 2016,第10期

机译：低Beclin-1表达预测多发性骨髓瘤用免疫调节药物治疗的患者的总生存期提高，并将自噬抑制确定为有希望的潜在可药物治疗的新治疗靶标：奥地利骨髓瘤注册机构（AMR）的分析
4. Local Delivery of Immunomodulatory Drugs to Improve the Outcome of Islets Transplantation in Type 1 Diabetes [C] . Diana Velluto, Teresa De Toni, Vita Manzoli, Society for Biomaterials annual meeting and exposition . 2018

机译：免疫调节药物的局部递送可改善1型糖尿病患者胰岛移植的效果。
5. Safety and Efficacy of the Immunomodulatory Drug (IMiD) Lenalidomide in Patients with Lymphoma: Development of RU051417I - Phase I/II Open-Label Study of R-ICE (Rituximab-Ifosfamide-Carboplatin-Etoposide) with Lenalidomide [R2-ICE] in Patients with First-Relapse/Primary Refractory Diffuse Large B-Cell Lymphoma (DLBCL). [D] . Kasi, Pashtoon Murtaza. 2018

机译：免疫调节药物来那度胺在淋巴瘤患者中的安全性和有效性：RU051417I-R-ICE（利妥昔单抗-异环磷酰胺-卡铂-依托泊苷）与来那度胺[R2-ICE]的I / II期开放标签研究的进展初次复发/原发性难治性弥漫性大B细胞淋巴瘤（DLBCL）。
6. Repurposed immunomodulatory drugs for Covid-19 in pre-ICu patients - mulTi-Arm Therapeutic study in pre-ICu patients admitted with Covid-19 – Repurposed Drugs (TACTIC-R): A structured summary of a study protocol for a randomised controlled trial [O] . Spoorthy Kulkarni, Marie Fisk, Michalis Kostapanos, -1

机译：用于ICU前期患者的Covid-19改用的免疫调节药物-接受Covid-19的ICU前患者的mulTi-Arm治疗研究–改用药物（TACTIC-R）：一项针对随机对照试验的研究方案的结构摘要
7. Role of Inflammatory Cytokines in COVID-19 Patients: A Review on Molecular Mechanisms, Immune Functions, Immunopathology and Immunomodulatory Drugs to Counter Cytokine Storm [O] . Ali A. Rabaan, Shamsah H. Al-Ahmed, Javed Muhammad, 2021

机译：炎症细胞因子在Covid-19患者中的作用：分子机制，免疫功能，免疫病理学和免疫调节药中的审查，以反对细胞因子风暴
8. Effects of Immunomodulatory Drugs on T Lymphocyte Activation and Function. [R] . Tsoukas, C. 1989

机译：免疫调节药物对T淋巴细胞活化和功能的影响。

Novel immunomodulatory drugs and neo-substrates

摘要

著录项

相似文献

相关主题

期刊订阅