Diagnostic Performance of Serum Human Epididymis Protein 4 (HE4) for Prediction of Malignancy in Ovarian Masses

机译：血清人附睾蛋白4（HE4）对卵巢癌恶性程度的预测诊断价值

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摘要

Early diagnosis of ovarian cancer is essential for long term disease control and mortality reduction. This has been achieved using tumor markers like cancer antigen 125 (CA-125) which is elevated in malignant as well as non-malignant conditions. This dilemma led to efforts towards development of newer markers like serum human epididymis secretory protein E4 (HE4). Present study aimed to evaluate role of HE4 in diagnosing ovarian cancers and comparing it with CA-125.

机译：卵巢癌的早期诊断对于长期控制疾病和降低死亡率至关重要。这是通过使用在恶性和非恶性疾病中升高的肿瘤标志物如癌症抗原125（CA-125）来实现的。这种困境导致人们努力开发新的标记物，例如血清人附睾分泌蛋白E4（HE4）。目前的研究旨在评估HE4在诊断卵巢癌中的作用并将其与CA-125进行比较。

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期刊名称 Asian Pacific Journal of Cancer Prevention : APJCP
作者
Rupali Dewan; Abhinav Dewan; Meera Jindal; Mausumi Bhardawaj;
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作者单位

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年(卷),期 2019(20),4
年度 2019
页码 -1
总页数 6
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
Ovarian masses; malignancy; human epididymis secretory protein E4; CA-125;

机译：卵巢肿块;恶性;人附睾分泌蛋白E4;CA-125;

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专利

1. Diagnostic Performance of Serum Human Epididymis Protein 4 (HE4) for Prediction of Malignancy in Ovarian Masses [J] . Rupali Dewan, Abhinav Dewan, Meera Jindal, Asian Pacific Journal of Cancer Prevention . 2019,第4期

机译：血清人附睾蛋白4（HE4）对卵巢癌恶性程度的预测诊断价值
2. Evaluation of human epididymis protein 4 (HE4) and Risk of Ovarian Malignancy Algorithm (ROMA) as diagnostic tools of type I and type II epithelial ovarian cancer in Japanese women [J] . Fujiwara Hiroyuki, Suzuki Mitsuaki, Takeshima Nobuhiro, Tumour biology : . 2015,第2期

机译：评估人类附睾蛋白4（HE4）和卵巢恶性算法（ROMA）作为日本女性I型和II型上皮性卵巢癌的诊断工具的风险
3. The diagnostic accuracy of two human epididymis protein 4 (HE4) testing systems in combination with CA125 in the differential diagnosis of ovarian masses [J] . Miriam Lenhard, Petra Stieber, Linda Hertlein Clinical chemistry and laboratory medicine: CCLM . 2011,第12期

机译：两种人附睾蛋白4（HE4）检测系统与CA125结合在卵巢肿块鉴别诊断中的诊断准确性
4. An Automatic Relevance Determination Method for Identifying the Signature of Stage I Ovarian Cancer in the Mass-Spectrum of Serum Proteins [C] . Jack K. Horner International Conference on Artificial Intelligence(ICAI'05) vol.2; 20050627-30; Las Vegas,NV(US) . 2005

机译：在血清蛋白质谱中识别I期卵巢癌特征的自动相关性确定方法
5. The implications of molecular diagnostics in clinicopathologic correlations in two disease processes: PSA serum levels in acute illnesses, and, prevalence of activated protein C resistance and factor V mutation in patients with thrombosis and in control patients by ethnic group. [D] . Honda, Stacey Ann Akemi. 2002

机译：分子诊断在两种疾病过程中的临床病理相关性中的意义：急性疾病中PSA血清水平，以及血栓形成患者和对照患者（按种族）的活化蛋白C抗性和因子V突变的患病率。
6. Serum human epididymis protein 4 (HE4) and Risk for Ovarian Malignancy Algorithm (ROMA) as new diagnostic and prognostic tools for epithelial ovarian cancer management [O] . Elisabetta Bandiera, Chiara Romani, Claudia Specchia, -1

机译：血清人物附睾蛋白4（HE4）和卵巢恶性算法（ROMA）作为上皮性卵巢癌管理的新诊断和预后工具
7. Evaluation of human epididymis protein 4 (HE4) and Risk of Ovarian Malignancy Algorithm (ROMA) as diagnostic tools of type I and type II epithelial ovarian cancer in Japanese women [O] . Hiroyuki Fujiwara, Mitsuaki Suzuki, Nobuhiro Takeshima, 2014

机译：评估人类附睾蛋白4（HE4）和卵巢恶性算法（ROMA）作为日本女性I型和II型上皮性卵巢癌的诊断工具的风险

Diagnostic Performance of Serum Human Epididymis Protein 4 (HE4) for Prediction of Malignancy in Ovarian Masses

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