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Normalizing Adverse Events using Recurrent Neural Networks with Attention

机译:使用注意力的递归神经网络对不良事件进行归一化

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摘要

Adverse events (AEs) are undesirable outcomes of medication administration and cause many hospitalizations as well as even deaths per year. Information about AEs can enable their prevention. Natural language processing (NLP) techniques can identify AEs from narratives and match them to a structured terminology. We propose a novel neural network for AE normalization utilizing bidirectional long short-term memory (biLSTM) with attention mechanism that generalizes to diverse datasets. We train this network to first learn a framework for general AE normalization and then to learn the specifics of the task on individual corpora. Our results on the datasets from the Text Analysis Conference (TAC) 2017-ADR track, FDA adverse drug event evaluation shared task, and the Social Media Mining for Health Applications Workshop & Shared Task 2019 show that our approach outperforms widely used rule-based normalizers on a diverse set of narratives. Additionally, it outperforms the best normalization system by 4.86 in macro-averaged F1-score in the TAC 2017-ADR track.
机译:不良事件(AEs)是药物管理的不良结果,每年都会导致许多住院甚至死亡。有关AE的信息可以使其预防。自然语言处理(NLP)技术可以从叙述中识别AE,并将其与结构化术语匹配。我们提出了一种利用双向长短期记忆(biLSTM)与注意力机制推广到各种数据集的新颖的AE归一化神经网络。我们训练该网络首先学习通用AE标准化的框架,然后再学习各个语料库上任务的细节。我们在2017年文本分析会议(TAC)-ADR跟踪,FDA不良药物事件评估共享任务以及2019年健康应用社交媒体挖掘研讨会和共享任务的数据集上的结果表明,我们的方法优于基于规则的规范化工具各种不同的叙述。此外,它在TAC 2017-ADR轨道的宏观平均F1得分方面胜过最佳归一化系统4.86。

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