Tacr3 in the lateral habenula differentially regulates orofacial allodynia and anxiety-like behaviors in a mouse model of trigeminal neuralgia

摘要

The time course of orofacial allodynia after pT-ION. pT-ION–induced primary allodynia in the ipsilateral V2 skin and secondary allodynia in the ipsilateral V3 skin as shown by reduced threshold to mechanical stimuli. Secondary cold allodynia was also induced in the V3 skin as shown by increased duration of wiping in response to acetone stimulation .  = 8 per group, ***