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Effects of enhancing agents on detection of cytomegalovirus in clinical specimens.

机译:增强剂对临床标本中巨细胞病毒检测的影响。

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摘要

Dimethyl sulfoxide, dexamethasone, and calcium were tested in combination for their enhancing effects on cytomegalovirus detection in shell vial cultures on 1,579 clinical specimens obtained primarily from adult solid-organ transplant recipients. Fluorescent-focus counts were elevated for the cytomegalovirus-positive urine specimens (P < 0.01) and throat washings (P < 0.05) but not for the tissue biopsy or blood samples. Epidermal growth factor also increased focus counts but provided no additional benefit when used in combination with the other agents. The triple-combination treatment did not increase the number of positive specimens identified.
机译:在主要从成年实体器官移植受者获得的1,579个临床标本上,对二甲基亚砜,地塞米松和钙对壳小瓶培养物中巨细胞病毒检测的增强作用进行了组合测试。巨细胞病毒阳性尿标本(P <0.01)和咽喉冲洗液(P <0.05)的荧光聚焦计数升高,但组织活检或血液样品的荧光聚焦计数却没有升高。表皮生长因子也增加了病灶数,但与其他药物联合使用时未提供其他益处。三重结合治疗并未增加鉴定出的阳性标本的数量。

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