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Plasma Pharmacokinetic Characteristics of Risperidone and Their Relationship to Saliva Concentrations in Children with Psychiatric or Neurodevelopmental Disorders

机译：利培酮的血浆药代动力学特征及其与精神病或神经发育障碍儿童唾液浓度的关系

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摘要

BackgroundRisperidone is a second-generation antipsychotic agent widely used in the treatment of schizophrenia and other psychotic disorders in adults. Risperidone is probably the most frequently used atypical antipsychotic in the pediatric population.

机译：背景利培酮是第二代抗精神病药，广泛用于治疗成人的精神分裂症和其他精神病。利培酮可能是儿童人群中最常用的非典型抗精神病药。

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期刊名称 other
作者
Michael G. Aman; Alexander A. Vinks; Bart Remmerie; Erik Mannaert; Yaser Ramadan; Jessica Masty; Ronald L. Lindsay; Krista Malone;
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作者单位

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年(卷),期 -1(29),7
年度 -1
页码 1476–1486
总页数 16
原文格式 PDF
正文语种
中图分类
关键词
risperidone children pharmacokinetics saliva plasma 9-hydroxyrisperidone enantiomers;

机译：利培酮;儿童;药代动力学;唾液;血浆;9-羟基利培酮对映体;

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专利

1. Plasma pharmacokinetic characteristics of risperidone and their relationship to saliva concentrations in children with psychiatric or neurodevelopmental disorders. [J] . Aman MG, Vinks AA, Remmerie B, Clinical therapeutics . 2007,第7期

机译：利培酮的血浆药代动力学特征及其与精神病或神经发育障碍儿童唾液浓度的关系。
2. Relationship between Risperidone and 9-hydroxy-risperidone Plasma Concentrations and CYP2D6 Enzyme Activity in Psychiatric Patients. [J] . Berecz R, LLerena A, De La Rubia A, Pharmacopsychiatry . 2002,第6期

机译：精神病患者利培酮和9-羟基-利培酮血浆浓度与CYP2D6酶活性之间的关系。
3. Population pharmacokinetics of oral risperidone in children, adolescents and adults with psychiatric disorders. [J] . Thyssen A, Vermeulen A, Fuseau E, Clinical pharmacokinetics . 2010,第7期

机译：口服利培酮在患有精神疾病的儿童，青少年和成人中的群体药代动力学。
4. Biomarkers of autism spectrum disorders (ASD) based on the comparative analysis of the metabolite concentrations in saliva [C] . Keiji Gamoh, Yoshinori Nishiwaki International Mass Spectrometry Conference . 2014

机译：基于唾液中代谢产物浓度的对比分析的自闭症谱系障碍（ASD）的生物标志物
5. Determination of the Levels and Concentrations of the Most Used Autism Spectrum Disorder Medications (Olanzapine, Risperidone and Quetiapine) in Autistic Patient’s Plasma by Using Lc/Ms/Ms [D] . Fraih, Dana Fayez. 2020

机译：通过使用LC / MS / MS测定自闭症患者血浆中最常用的自闭症谱系药物（Olanzapine，Risperidone和Quetiapine）的水平和浓度
6. Plasma Concentrations of BDNF and IGF-1 in Abstinent Cocaine Users with High Prevalence of Substance Use Disorders: Relationship to Psychiatric Comorbidity [O] . María Pedraz, Ana Isabel Martín-Velasco, Nuria García-Marchena, -1

机译：禁忌可卡因使用者中的BDNF和IGF-1的血浆浓度与物质使用障碍的高患病率：与精神病合并症的关系
7. Plasma Pharmacokinetic Characteristics of Risperidone and Their Relationship to Saliva Concentrations in Children with Psychiatric or Neurodevelopmental Disorders [O] . Michael G. Aman, Alexander A. Vinks, Bart Remmerie, 2007

机译：血浆药代动力学特征及精神病或神经发育障碍儿童唾液浓度的关系及其关系

Plasma Pharmacokinetic Characteristics of Risperidone and Their Relationship to Saliva Concentrations in Children with Psychiatric or Neurodevelopmental Disorders

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