Surgical Suturing of Articular Cartilage Induces Osteoarthritis-Like Changes

摘要

IntroductionIn clinical tissue-engineering-based approaches to articular cartilage repair, various types of flaps are frequently used to retain an implanted construct within the defect, and they are usually affixed by suturing. We hypothesize that the suturing of articular cartilage is associated with a loss of chondrocytes from and osteoarthritis-like changes within the peri-sutural area.