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Restoration of accommodation: surgical options for correction of presbyopia

机译:恢复住宿:矫正老花眼的外科手术选择

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摘要

Accommodation is a dioptric change in the power of the eye to see clearly at near. Ciliary muscle contraction causes a release in zonular tension at the lens equator, which permits the elastic capsule to mould the young lens into an accommodated form. Presbyopia, the gradual age-related loss of accommodation, occurs primarily through a gradual age-related stiffening of the lens. While there are many possible options for relieving the symptoms of presbyopia, only relatively recently has consideration been given to surgical restoration of accommodation to the presbyopic eye. To understand how this might be achieved, it is necessary to understand the accommodative anatomy, the mechanism of accommodation and the causes of presbyopia. A variety of different kinds of surgical procedures has been considered for restoring accommodation to the presbyopic eye, including surgical expansion of the sclera, using femtosecond lasers to treat the lens or with so-called accommodative intraocular lenses (IOLs). Evidence suggests that scleral expansion cannot and does not restore accommodation. Laser treatments of the lens are in their early infancy. Development and testing of accommodative IOLs are proliferating. They are designed to produce a myopic refractive change in the eye in response to ciliary muscle contraction either through a movement of an optic or through a change in surface curvature. Three general design principles are being considered. These are single optic IOLs that rely on a forward shift of the optic, dual optic IOLs that rely on an increased separation between the two optics, or IOLs that permit a change in surface curvature to produce an increase in optical power in response to ciliary muscle contraction. Several of these different IOLs are available and being used clinically, while many are still in research and development.
机译:调节是屈光度的变化,在近处清晰可见。睫状肌收缩引起晶状体赤道的小带张力的释放,这允许弹性囊将年轻的晶状体模制成容纳的形式。老花眼是与年龄有关的渐进性适应障碍,主要是由于与年龄有关的晶状体逐渐变硬而引起的。尽管有许多可能的方法可以减轻老花眼的症状,但是直到最近才考虑通过外科手术恢复老花眼的适应性。要了解如何实现此目的,有必要了解适应性解剖结构,调节机制以及老花眼的原因。已经考虑了各种不同种类的外科手术程序来恢复老花眼的适应性,包括巩膜的外科手术扩张,使用飞秒激光治疗晶状体或使用所谓的适应性人工晶状体(IOL)。有证据表明巩膜扩张不能而且不能恢复适应性。镜片的激光治疗尚处于早期阶段。适应性IOL的开发和测试正在激增。它们被设计为通过视神经的移动或通过表面曲率的变化,响应于睫状肌收缩而在眼睛中产生近视屈光变化。正在考虑三个通用设计原则。这些是依赖于光学器件向前移动的单光学IOL,依赖于两个光学器件之间增加的间距的双光学IOL,或者允许表面曲率发生变化以响应睫状肌而增加光焦度的IOL收缩。这些不同的IOL中有几种可用并在临床上使用,而许多仍在研发中。

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