Investigation of Hyperpolarized 3He MRI Utility in Examining Human Airway Diameter Behavior in Asthma through Comparison with High-Resolution Computed Tomography

摘要

Rationale and ObjectivesApplication of a previously developed model-based algorithm on hyperpolarized (HP) ³He MR dynamic projection images of phantoms was extended to investigate the utility of HP ³He MRI in quantifying airway caliber change associated with asthma.