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Adjuvant radioimmunotherapy trial with iodine-131-labeled anti-carcinoembryonic antigen monoclonal antibody F6 F(ab)2 after resection of liver metastases from colorectal cancer

机译：碘131标记的抗癌胚抗原单克隆抗体F6 F（ab）2辅助结直肠癌切除肝转移后的放射免疫治疗试验

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摘要

PurposeTo evaluate the feasibility of radioimmunotherapy (RIT) with radiolabeled anti-CEA antibodies after complete resection of liver metastases (LM) from colorectal cancer.

机译：目的在彻底切除结直肠癌的肝转移瘤（LM）后，评估采用放射标记的抗CEA抗体进行放射免疫疗法（RIT）的可行性。

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期刊名称 other
作者
Marc Ychou; David Azria; Cathy Menkarios; Patrick Faurous; François Quenet; Bernard Saint-Aubert; Philippe Rouanet; Monique Pèlegrin; Caroline Bascoul-Mollevi; Dominique Guerreau; Jean-Claude Saccavini; Jean-Pierre Mach; Jean-Claude Artus; André Pèlegrin;
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年(卷),期 -1(14),11
年度 -1
页码 3487–3493
总页数 19
原文格式 PDF
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关键词
Adenocarcinoma mortality radiotherapy secondary Adult Antibodies Monoclonal therapeutic use Carcinoembryonic Antigen immunology Chemotherapy Adjuvant Colorectal Neoplasms mortality pathology therapy Female Hepatectomy Humans Immunoglobulin Fab Fragments therapeutic use Iodine Radioisotopes pharmacokinetics therapeutic use Liver Neoplasms Male Middle Aged Radioimmunotherapy methods Radiotherapy Adjuvant;

机译：腺癌;死亡率;放射治疗;次生;成人;抗体;单克隆;治疗用途;癌胚抗原;免疫学;化学疗法;佐剂;结直肠肿瘤;死亡率;病理学;治疗;女性;肝切除术;人类;免疫球蛋白Fab片段;治疗用途;碘放射性同位素;药代动力学;治疗用途;肝肿瘤;男性;中年;放射免疫疗法;方法;放射疗法;佐剂;

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专利

1. Adjuvant Radioimmunotherapy Trial with Iodine-131-Labeled Anti-Carcinoembryonic Antigen Monoclonal Antibody F6 F(ab')2 after Resection of Liver Metastases from Colorectal Cancer. [J] . Ychou M, Azria D, Menkarios C, Clinical cancer research: an official journal of the American Association for Cancer Research . 2008 ,第11期

机译：结直肠癌切除肝转移后，用碘131标记的抗癌胚抗原单克隆抗体F6 F（ab'）2进行辅助放射免疫治疗试验。
2. Radioimmunotherapy of small-volume disease of metastatic colorectal cancer: Results of a phase II trial with the iodine-131-labeled humanized anti-carcinoembryonic antigen antibody hMN-14 (Retraction of vol 94, pg 1373, 2002) [J] . Behr T. M., Liersch T., Greiner-Bechert L., Cancer: A Journal of the American Cancer Society . 2015 ,第13期

机译：转移性大肠癌小剂量疾病的放射免疫疗法：碘131标记的人源化抗癌胚抗原抗体hMN-14的II期试验的结果（第94卷撤消，第1373页，2002年）
3. Dose escalation trial of indium-111-labeled anti-carcinoembryonic antigen chimeric monoclonal antibody (chimeric T84.66) in presurgical colorectal cancer patients. [J] . Wong JY, Chu DZ, Yamauchi D, The Journal of Nuclear Medicine . 1998 ,第12期

机译：铟111标记的抗癌胚抗原嵌合单克隆抗体（嵌合T84.66）在大肠癌前期患者的剂量递增试验。
4. Recurrence Patterns After Resection of Liver Metastases from Colorectal Cancer [C] . Halfdan Sorbye St. Gallen EORTC Gastrointestinal Cancer Conference . 2014

机译：从结肠直肠癌切除肝脏转移后的复发模式
5. Self-Assembled Antibody Nanorings as Prosthetic Antigen Receptors for Redirecting T Cells against Tumor Cells and as Platform for Delivery of Vaccine Adjuvants for Cancer Immunotherapy. [D] . Shen, Jingjing. 2016

机译：自组装的抗体纳米环作为修复性抗原受体，用于针对肿瘤细胞重定向T细胞，并作为用于癌症免疫治疗的疫苗佐剂的递送平台。
6. Adjuvant hepatic arterial infusion pump chemotherapy and resection versus resection alone in patients with low-risk resectable colorectal liver metastases – the multicenter randomized controlled PUMP trial [O] . F. E. Buisman, M. Y. V. Homs, D. J. Grünhagen, 2019

机译：低风险可切除结直肠肝转移患者的辅助肝动脉输液泵化疗和切除与单纯切除–多中心随机对照PUMP试验
7. Adjuvant Radioimmunotherapy Trial with Iodine-131-Labeled Anti-Carcinoembryonic Antigen Monoclonal Antibody F6 F(ab')2 after Resection of Liver Metastases from Colorectal Cancer. [O] . Ychou, Marc, Azria, David, Menkarios, Cathy, 2008

机译：结直肠癌切除肝转移后，用碘131标记的抗癌胚抗原单克隆抗体F6 F（ab'）2进行辅助放射免疫治疗试验。

Adjuvant radioimmunotherapy trial with iodine-131-labeled anti-carcinoembryonic antigen monoclonal antibody F6 F(ab)2 after resection of liver metastases from colorectal cancer

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