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DIRECT NUMERICAL SIMULATION OF TRANSITIONAL FLOW IN A STENOSED CAROTID BIFURCATION

机译:狭窄颈动脉分叉中过渡流动的直接数值模拟

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摘要

The blood flow dynamics of a stenosed, subject-specific, carotid bifurcation were numerically simulated using the spectral element method. Pulsatile inlet conditions were based on in vivo color Doppler ultrasound measurements of blood velocity. The results demonstrated the transitional or weakly turbulent state of the blood flow, which featured rapid velocity and pressure fluctuations in the post-stenotic region of the internal carotid artery during systole and laminar flow during diastole. High-frequency vortex shedding was greatest downstream of the stenosis during the deceleration phase of systole. Velocity fluctuations had a frequency within the audible range of 100–300 Hz. Instantaneous wall shear stress within the stenosis was relatively high during systole (~25-45 Pa) compared to that in a healthy carotid. In addition, high spatial gradients of wall shear stress were present due to flow separation on the inner wall. Oscillatory flow reversal and low pressure were observed distal to the stenosis in the internal carotid artery. This study predicts the complex flow field, the turbulence levels and the distribution of the biomechanical stresses present in vivo within a stenosed carotid artery.
机译:使用频谱元素方法对狭窄的,特定于受试者的颈动脉分叉的血流动力学进行了数值模拟。脉搏进入条件是基于体内彩色多普勒超声测量的血流速度。结果表明,血流处于过渡或弱湍流状态,其特征是在收缩期期间颈内动脉狭窄后区域的速度和压力快速波动,在舒张期出现层流。在收缩期减速阶段,高频旋涡脱落在狭窄的下游。速度波动的频率在100-300 Hz的可听范围内。与健康颈动脉相比,狭窄时的瞬时壁切应力相对较高(约25-45 Pa)。另外,由于内壁上的流动分离,壁剪切应力存在较高的空间梯度。在颈内动脉狭窄远端观察到振荡血流逆转和低压。这项研究预测了狭窄的颈动脉体内的复杂流场,湍流水平和生物力学应力的分布。

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