CHLOROTHALONIL EXPOSURE AND CANCER INCIDENCE AMONG PESTICIDE APPLICATOR PARTICIPANTS IN THE AGRICULTURAL HEALTH STUDY

摘要

BackgroundChlorothalonil is a broad spectrum, non-systemic fungicide widely used to control diseases affecting over 50 fruit, vegetable and agricultural crops. Despite its extensive use for over 30 years, little is known about the potential human carcinogenicity associated with the routine application of chlorothalonil. Rodent studies have shown evidence of renal tubular carcinomas and adenomas. We explored cancer incidence with chlorothalonil exposure using data from the Agricultural Health Study, a prospective cohort of licensed pesticide applicators in Iowa and North Carolina.