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The Importance of Organ Geometry and Boundary Constraints for Planning of Medical Interventions

机译:器官几何形状和边界约束对于医疗干预计划的重要性

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摘要

Realistic modeling of medical interventions involving tool-tissue interactions has been considered to be a key requirement in the development of high-fidelity simulators and planners. Organ geometry, the soft-tissue constitutive laws, and boundary conditions imposed by the connective tissues surrounding the organ are some of the factors that govern the accuracy of medical intervention planning. In this study it is demonstrated that (for needle path planning) the organ geometry and boundary constraints surrounding the organ are the most important factors inuencing the deformation. As an example, the procedure of needle insertion into the prostate (e.g. for biopsy or brachytherapy) is considered. Image segmentation is used to extract the anatomical details from magnetic resonance images, while object-oriented finite element analysis (OOF) software is used to generate finite element (FE) meshes from the segmented images. Two-dimensional FE simulations that account for complex anatomical details along with relative motion between the prostate and its surrounding structure using cohesive zone models are compared with traditional simulation models having simple organ geometry and boundary constraints. Nodal displacements for these simpler models were observed to be up to 14 times larger than those obtained from the anatomically accurate models.
机译:涉及工具-组织相互作用的医学干预措施的逼真建模已被认为是开发高保真模拟器和计划器的关键要求。器官的几何形状,软组织本构律以及器官周围结缔组织施加的边界条件是决定医疗干预计划准确性的一些因素。在这项研究中,证明了(对于针路径规划)器官的几何形状和器官周围的边界约束是影响变形的最重要因素。例如,考虑将针插入前列腺的过程(例如用于活检或近距离放射治疗)。图像分割用于从磁共振图像中提取解剖学细节,而面向对象的有限元分析(OOF)软件则用于从分割的图像生成有限元(FE)网格。使用粘性区域模型将考虑复杂解剖细节以及前列腺及其周围结构之间的相对运动的二维有限元模拟与具有简单器官几何形状和边界约束的传统模拟模型进行了比较。观察到这些较简单模型的节点位移比从解剖学精确模型获得的节点位移大14倍。

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