The objective of this paper is to present two methods to extend the response range of laser speckle imaging (LSI). We report on the use of two methods (image exposure time control and magnetomotive actuation of exogenous contrast agents) to enhance characterization of high- and low-flow vasculature, respectively. With an exposure time of 10 and 0.01 ms, the linear response range extended to 10 and 280 mm/s, respectively. With application of an AC magnetic field to a solution of stagnant SPIO particles, an apparent increase of ~3× in speckle flow index was induced.
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机译：本文的目的是提出两种扩展激光散斑成像（LSI）响应范围的方法。我们报告了使用两种方法（图像曝光时间控制和外源性造影剂的磁动驱动）来分别增强高流量和低流量脉管系统的特性。曝光时间为10和0.01 ms时，线性响应范围分别扩展到10和280 mm / s。通过将交流磁场施加于停滞的SPIO颗粒溶液，可以使斑点流动指数明显增加〜3倍。
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