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Controlling for Drug Dose in Systematic Review and Meta-Analysis: A Case Study of the Effect of Antidepressant Dose

机译：系统评价和荟萃分析中药物剂量的控制：以抗抑郁药的作用为例

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摘要

PurposeTo describe a method for quantitatively dealing with drug dose in comparative effectiveness reviews. Second-generation antidepressants are used as an example to illustrate this method, and to determine whether dose influences conclusions on comparative effectiveness.

机译：目的描述在比较有效性审查中定量处理药物剂量的方法。以第二代抗抑郁药为例来说明这种方法，并确定剂量是否会影响比较效果的结论。

著录项

期刊名称 other
作者
Richard A. Hansen; Charity G. Moore; Stacie B. Dusetzina; Brian I. Leinwand; Gerald Gartlehner; Bradley N. Gaynes;
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作者单位

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年(卷),期 -1(29),1
年度 -1
页码 91–103
总页数 17
原文格式 PDF
正文语种
中图分类
关键词
meta-analysis meta-regression dose dose-response comparative effectiveness;

机译：荟萃分析;荟萃回归;剂量;剂量反应;比较有效性;

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专利

1. Controlling for drug dose in systematic review and meta-analysis: a case study of the effect of antidepressant dose. [J] . Hansen RA, Moore CG, Dusetzina SB, Medical decision making: An international journal of the Society for Medical Decision Making . 2009,第1期

机译：在系统评价和荟萃分析中控制药物剂量：以抗抑郁药剂量的作用为例。
2. Adverse Drug Events Associated with Low-Dose (10?mg) Versus High-Dose (25?mg) Empagliflozin in Patients Treated for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials [J] . Xia Dai, Zu-chun Luo, Lu Zhai, Diabetes therapy . 2018,第2期

机译：与2型糖尿病患者低剂量（10？mg）与高剂量（25？mg）依帕列净相关的不良药物事件：随机对照试验的系统评价和荟萃分析
3. Drop-out rates in placebo-controlled trials of antidepressant drugs: A systematic review and meta-analysis based on clinical study reports [J] . Tarang Sharma, Louise Schow Guski, Nanna Freund, The International journal of risk & safety in medicine. . 2019,第4期

机译：抗抑郁药物安慰剂对照试验中的辍学率：基于临床研究报告的系统综述与荟萃分析
4. Antidepressants, Cognitive-Behavior Therapy And Combination Treatment For Depressed Patients: A Systematic Review And Meta-Analysis [C] . Wallace J., Byrne C., Nwosu B., Interdisciplinary Congress of the Hellenic Society for the Advancement ofPsychiatry and Related Sciences . 2014

机译：抑郁症患者的抗抑郁药，认知行为治疗和组合治疗：系统审查和荟萃分析
5. Analysis and application of bio-erodible swelling polymers in the development of controlled -release matrix systems for low-dose BCS class 2 drugs, using glipizide as a model drug [D] . Jamzad, Shahla 2006

机译：以格列吡嗪为模型药物的生物易蚀溶胀聚合物在低剂量BCS 2类药物控释基质系统开发中的分析和应用
6. Adverse Drug Events Associated with Low-Dose (10 mg) Versus High-Dose (25 mg) Empagliflozin in Patients Treated for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials [O] . Xia Dai, Zu-chun Luo, Lu Zhai, 2018

机译：小剂量（10 mg）与大剂量（25 mg）依格列净相关的不良药物事件在2型糖尿病患者中的治疗：系统评价和随机对照试验的荟萃分析
7. Adverse Drug Events Associated with Low-Dose (10 mg) Versus High-Dose (25 mg) Empagliflozin in Patients Treated for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials [O] . Xia Dai, Zu-chun Luo, Lu Zhai, 2018

机译：与低剂量（10mg）与高剂量（25mg）Empagliflozin的不良药物发生在2型糖尿病的患者中：随机对照试验的系统审查和荟萃分析

Controlling for Drug Dose in Systematic Review and Meta-Analysis: A Case Study of the Effect of Antidepressant Dose

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