A DOUBLE-BLIND RANDOMIZED CONTROLLED TRIAL OF OLANZAPINE PLUS SERTRALINE VERSUS OLANZAPINE PLUS PLACEBO FOR PSYCHOTIC DEPRESSION -- THE STOP-PD STUDY

摘要

Context:Expert guidelines recommend that the pharmacological treatment of major depression with psychotic features (MDpsy) combines antidepressant with antipsychotic medications. However, evidence for the efficacy of combination pharmacotherapy has been limited and without positive trials in geriatric patients.