Genomic and mutational profiling to assess clonal relationships between multiple non-small cell lung cancers

摘要

PurposeIn cases of multiple non-small cell lung cancer (NSCLC), clinicians must decide whether patients have independent tumors or metastases and tailor treatment accordingly. Decisions are currently made using the Martini and Melamed criteria, which are mostly based on tumor location and histological type. New genomic tools could improve the ability to assess tumor clonality.