Engraftment of Syngeneic and Allogeneic Endothelial Cells Hepatocytes and Cholangiocytes into Partially Hepatectomized Rats Previously Treated with Mitomycin C

摘要

BackgroundPretreatment with retrorsine crosslinks host hepatocyte DNA and prevents proliferation after partial hepatectomy (PH), allowing selective expansion of transplanted progenitors. Shortcomings are length of protocol and carcinogenicity of retrorsine.