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A PHASE II TRIAL OF SURGERY WITH PERIOPERATIVE INGN 201 (Ad5CMV-p53) GENE THERAPY FOLLOWED BY CHEMORADIOTHERAPY FOR ADVANCED RESECTABLE SQUAMOUS CELL CARCINOMA OF THE ORAL CAVITY OROPHARYNX HYPOPHARYNX AND LARYNX: REPORT OF THE SOUTHWEST ONCOLOGY GROUP

机译：围手术期INGN外科杂志II期试验201（ad5CmV-p53基因）基因治疗随后放化疗aDVaNCED口腔口咽下咽和喉可切除鳞状细胞癌：西南肿瘤组的报告

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ObjectiveTo assess the feasibility of treating high risk, selected Stage III and IV squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx with perioperative INGN 201 gene therapy along with surgery and chemoradiation in a multi-institutional setting.

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期刊名称 other
作者
George H. Yoo; James Moon; Michael LeBlanc; Fulvio Lonardo; Susan Urba; Harold Kim; Ehab Hanna; Terry Tsue; Joseph Valentino; John Ensley; Gregory Wolf;
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年(卷),期 -1(135),9
年度 -1
页码 869–874
总页数 12
原文格式 PDF
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1. A phase 2 trial of surgery with perioperative INGN 201 (Ad5CMV-p53) gene therapy followed by chemoradiotherapy for advanced, resectable squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx: report of the Southwest Oncology Group. [J] . Yoo GH, Moon J, Leblanc M Archives of otolaryngology--head & neck surgery. . 2009,第9期

机译：围手术期INGN 201（Ad5CMV-p53）基因治疗并放化疗治疗晚期可切除的口腔鳞状细胞癌，口咽，下咽和喉癌的2期手术试验：西南肿瘤学小组的报告。
2. Phase II trial of chemoradiation for organ preservation in resectable stage III or IV squamous cell carcinomas of the larynx or oropharynx: results of Eastern Cooperative Oncology Group Study E2399. [J] . Cmelak AJ, Li S, Goldwasser MA, Journal of Clinical Oncology . 2007,第25期

机译：在可切除的喉或口咽的III或IV期鳞状细胞癌中进行化学放射治疗器官保存的II期临床试验：东部合作肿瘤小组研究E2399的结果。
3. Long-term Survival of locally advanced Squamous Cell Carcinoma of the Oropharynx, Hypopharynx and Larynx after definitive Chemoradiotherapy in 3D and IMRT Technique [J] . Abu Jawad J., Sahin Z., Poettgen C., Strahlentherapie und Onkologie . 2016,第Suppla1期

机译：3D和IMRT技术明确的化学疗法后欧咽，后咽癌和喉局部晚期鳞状细胞癌的长期存活
4. PHASE I/II TRIAL OF DUAL AGENT POLYAMINE DEPLETION THERAPY FOR FELINE ORAL SQUAMOUS CELL CARCINOMA [C] . Katherine A Skorupski, Thomas OBrien, Mark Burns, Annual conference of the Veterinary Cancer Society . 2008

机译：双药剂多胺耗竭治疗猫鳞状鳞状细胞癌的I / II试验
5. Randomized Phase III Trial of Induction Chemotherapy With Docetaxel Cisplatin and Fluorouracil Followed by Surgery Versus Up-Front Surgery in Locally Advanced Resectable Oral Squamous Cell Carcinoma [O] . Lai-ping Zhong, Chen-ping Zhang, Guo-xin Ren, -1

机译：多西他赛顺铂和氟尿嘧啶诱导化疗联合手术对局部晚期可切除口腔鳞状细胞癌的前期手术的随机III期试验。
6. Multimodal Intensification Regimens for Advanced, Resectable, Previously Untreated Squamous Cell Cancer of the Oral Cavity, Oropharynx, or Hypopharynx [O] . David E. Schuller, Enver Ozer, Amit Agrawal, 2007

机译：用于口腔，Oropharynx或Hypopharynx的先进，可重症，先前未经治疗的鳞状细胞癌的多峰强化方案
7. Combined Therapy for Non-Resectable Squamous Cell Carcinoma of the Oral Cavity. Local Selective Intra-Arterial Infusion with Adriamycin and Bleomycin Combined Concurrently with Radiotherapy. The Predictive Value of Flow Cytometry in Monitoring Cell Cycle Kinetic Effects of Therapy [R] . Noorman van der Dussen, M. F. 1986

机译：口腔不可切除鳞状细胞癌的联合治疗。局部选择性动脉内注射阿霉素和博来霉素联合放疗。流式细胞术在监测细胞周期动力学疗效中的预测价值

A PHASE II TRIAL OF SURGERY WITH PERIOPERATIVE INGN 201 (Ad5CMV-p53) GENE THERAPY FOLLOWED BY CHEMORADIOTHERAPY FOR ADVANCED RESECTABLE SQUAMOUS CELL CARCINOMA OF THE ORAL CAVITY OROPHARYNX HYPOPHARYNX AND LARYNX: REPORT OF THE SOUTHWEST ONCOLOGY GROUP

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