Adiponectin Inhibits Allograft Rejection in Murine Cardiac Transplantation

摘要

BackgroundLow levels of plasma adiponectin, an adipocytokine that possesses anti-inflammatory and anti-atherogenic properties, frequently observed among obese subjects correlate with higher prevalence of several cardiovascular diseases. This study investigated whether adiponectin modulates allograft rejection in MHC class II—mismatched cardiac transplants.