Breast Cancer Risk 55+ Years after Irradiation for an Enlarged Thymus and Its Implications for Early Childhood Medical Irradiation Today

摘要

PurposeRadiotherapy during childhood increases long-term cancer risk, but the risk from radiation as a result of relatively higher-dose diagnostic procedures remains less well known. This study, which evaluates breast cancer (BC) incidence in a cohort treated with “lower dose” chest radiotherapy (cRT) over 50 years ago, can assist with estimating lifetime BC risk in young children exposed to radiation from procedures such as chest computed tomography (CT) or treatment with recent “lower dose” cRT protocols