The potential impact of selective donor deferrals based on estimated blood volume on vasovagal reactions and donor deferral rates

摘要

BACKGROUNDWhole blood donation in the United States is restricted in volume to 10.5 mL/kg or less in an effort to prevent hypovolemic reactions, but still may exceed more than 15% of a donor’s estimated blood volume (EBV). We analyzed the association of EBV with prefaint and systemic vasovagal reactions (SVRs) among whole blood donors and the potential impact of an EBV-based deferral policy.