Computerized Algorithms: In Silico Testing—Impact on the Progress of the Closed Loop Insulin Infusion for Critically Ill Patients Project

摘要

BackgroundIn silico testing was used extensively in the European Commission-funded Closed Loop Insulin Infusion for Critically Ill Patients (Clinicip) project, which aimed to develop prototype systems for closed loop glucose control in the critically ill. This article presents two examples of how the simulation environment was utilized in this project.