Oxidatively Stable Aqueous Europium(II) Complexes through Steric and Electronic Manipulation of Cryptand Coordination Chemistry

摘要

A series of cryptands have been prepared and they demonstrate the relationship between oxidative stability of aqueous Eu^II and ligand properties (see figure). One of these Eu^II complexes is more stable than Fe^II in hemoglobin and appears to be the most oxidatively-stable aqueous Eu^II species known. The high stability of Eu^II is expected to enable the use of the unique magnetic and optical properties of this ion in vivo.